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Lck Mediates Th2 Differentiation through Effects on T-bet and GATA-3

The Src family kinase Lck has been shown to be crucial in T cell signaling and development. However, its role in Th effector functions is not well understood. Lck has previously been shown to play a role in the cytokine expression of Th2 cells, but the mechanism by which Lck influences Th2 effector...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Kemp, Kyeorda L., Levin, Steven D., Bryce, Paul J., Stein, Paul L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889130/
https://ncbi.nlm.nih.gov/pubmed/20237292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901282
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