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Chemical detoxification of small molecules by C. elegans

Caenorhabditis elegans lives in compost and decaying fruit, eats bacteria and is exposed to pathogenic microbes. We show that C. elegans is able to modify diverse microbial small-molecule toxins via both O-and N-glucosylation as well as unusual 3′-O-phosphorylation of the resulting glucosides. The r...

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Main Authors: Stupp, Gregory S., von Reuss, Stephan H., Izrayelit, Yevgeniy, Ajredini, Ramadan, Schroeder, Frank C., Edison, Arthur S.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747836/
https://ncbi.nlm.nih.gov/pubmed/23163740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300520u
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