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2D NMR-based metabolomics uncovers interactions between conserved biochemical pathways in the model organism Caenorhabditis elegans

Ascarosides are small-molecule signals that play a central role in C. elegans biology, including dauer formation, aging, and social behaviors, but many aspects of their biosynthesis remain unknown. Using automated 2D NMR-based comparative metabolomics, we identified ascaroside ethanolamides as shunt...

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Detalhes bibliográficos
Main Authors: Izrayelit, Yevgeniy, Robinette, Steven L., Bose, Neelanjan, von Reuss, Stephan H., Schroeder, Frank C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574178/
https://ncbi.nlm.nih.gov/pubmed/23163760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb3004644
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