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Chemical detoxification of small molecules by C. elegans

Caenorhabditis elegans lives in compost and decaying fruit, eats bacteria and is exposed to pathogenic microbes. We show that C. elegans is able to modify diverse microbial small-molecule toxins via both O-and N-glucosylation as well as unusual 3′-O-phosphorylation of the resulting glucosides. The r...

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Detalhes bibliográficos
Main Authors: Stupp, Gregory S., von Reuss, Stephan H., Izrayelit, Yevgeniy, Ajredini, Ramadan, Schroeder, Frank C., Edison, Arthur S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747836/
https://ncbi.nlm.nih.gov/pubmed/23163740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300520u
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