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Chemical detoxification of small molecules by C. elegans

Caenorhabditis elegans lives in compost and decaying fruit, eats bacteria and is exposed to pathogenic microbes. We show that C. elegans is able to modify diverse microbial small-molecule toxins via both O-and N-glucosylation as well as unusual 3′-O-phosphorylation of the resulting glucosides. The r...

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Bibliografiske detaljer
Main Authors: Stupp, Gregory S., von Reuss, Stephan H., Izrayelit, Yevgeniy, Ajredini, Ramadan, Schroeder, Frank C., Edison, Arthur S.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747836/
https://ncbi.nlm.nih.gov/pubmed/23163740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300520u
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