GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon

Short-chain fatty acids, generated in colon by bacterial fermentation of dietary fiber, protect against colorectal cancer and inflammatory bowel disease. Among these bacterial metabolites, butyrate is biologically most relevant. GPR109A is a G-protein-coupled receptor for nicotinate, but recognizes...

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Bibliographische Detailangaben
Hauptverfasser: Thangaraju, Muthusamy, Cresci, Gail A., Liu, Kebin, Ananth, Sudha, Gnanaprakasam, Jaya P., Browning, Darren D., Mellinger, John D., Smith, Sylvia B., Digby, Gregory J., Lambert, Nevin A., Prasad, Puttur D., Ganapathy, Vadivel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747834/
https://ncbi.nlm.nih.gov/pubmed/19276343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4466
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