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Fundus Autofluorescence in the Abca4(−/−) Mouse Model of Stargardt Disease—Correlation With Accumulation of A2E, Retinal Function, and Histology

PURPOSE. To investigate fundus autofluorescence (AF) characteristics in the Abca4(−/−) mouse, an animal model for AMD and Stargardt disease, and to correlate findings with functional, structural, and biochemical assessments. METHODS. Blue (488 nm) and near-infrared (790 nm) fundus AF images were qua...

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Main Authors: Charbel Issa, Peter, Barnard, Alun R., Singh, Mandeep S., Carter, Emma, Jiang, Zhichun, Radu, Roxana A., Schraermeyer, Ulrich, MacLaren, Robert E.
Format: Artigo
Jezik:Inglês
Izdano: The Association for Research in Vision and Ophthalmology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747716/
https://ncbi.nlm.nih.gov/pubmed/23761084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-11688
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