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Atg18 phosphoregulation controls organellar dynamics by modulating its phosphoinositide-binding activity
The PROPPIN family member Atg18 is a phosphoinositide-binding protein that is composed of a seven β-propeller motif and is part of the conserved autophagy machinery. Here, we report that the Atg18 phosphorylation in the loops in the propellar structure of blade 6 and blade 7 decreases its binding af...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3747300/ https://ncbi.nlm.nih.gov/pubmed/23940117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201302067 |
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