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Structure-based Analyses Reveal Distinct Binding Sites for Atg2 and Phosphoinositides in Atg18
Autophagy is an intracellular degradation system by which cytoplasmic materials are enclosed by an autophagosome and delivered to a lysosome/vacuole. Atg18 plays a critical role in autophagosome formation as a complex with Atg2 and phosphatidylinositol 3-phosphate (PtdIns(3)P). However, little is kn...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3442503/ https://ncbi.nlm.nih.gov/pubmed/22851171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.397570 |
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