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The Amyloid Precursor Protein (APP) Does Not Have a Ferroxidase Site in Its E2 Domain
The ubiquitous 24-meric iron-storage protein ferritin and multicopper oxidases such as ceruloplasmin or hephaestin catalyze oxidation of Fe(II) to Fe(III), using molecular oxygen as oxidant. The ferroxidase activity of these proteins is essential for cellular iron homeostasis. It has been reported t...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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Public Library of Science
2013
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3747053/ https://ncbi.nlm.nih.gov/pubmed/23977245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072177 |
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