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Self-assembly Is Prerequisite for Catalysis of Fe(II) Oxidation by Catalytically Active Subunits of Ferritin

Fe(III) storage by ferritin is an essential process of the iron homeostasis machinery. It begins by translocation of Fe(II) from outside the hollow spherical shape structure of the protein, which is formed as the result of self-assembly of 24 subunits, to a di-iron binding site, the ferroxidase cent...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ebrahimi, Kourosh Honarmand, Hagedoorn, Peter-Leon, Hagen, Wilfred R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646333/
https://ncbi.nlm.nih.gov/pubmed/26370076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.678375
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