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Self-assembly Is Prerequisite for Catalysis of Fe(II) Oxidation by Catalytically Active Subunits of Ferritin

Fe(III) storage by ferritin is an essential process of the iron homeostasis machinery. It begins by translocation of Fe(II) from outside the hollow spherical shape structure of the protein, which is formed as the result of self-assembly of 24 subunits, to a di-iron binding site, the ferroxidase cent...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Ebrahimi, Kourosh Honarmand, Hagedoorn, Peter-Leon, Hagen, Wilfred R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646333/
https://ncbi.nlm.nih.gov/pubmed/26370076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.678375
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