Cardiac nuclear high mobility group box 1 prevents the development of cardiac hypertrophy and heart failure

AIMS: High mobility group box 1 (HMGB1) is an abundant and ubiquitous nuclear DNA-binding protein that has multiple functions dependent on its cellular location. HMGB1 binds to DNA, facilitating numerous nuclear functions including maintenance of genome stability, transcription, and repair. However,...

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Autores principales: Funayama, Akira, Shishido, Tetsuro, Netsu, Shunsuke, Narumi, Taro, Kadowaki, Shinpei, Takahashi, Hiroki, Miyamoto, Takuya, Watanabe, Tetsu, Woo, Chang-Hoon, Abe, Jun-ichi, Kuwahara, Koichiro, Nakao, Kazuwa, Takeishi, Yasuchika, Kubota, Isao
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2013
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746952/
https://ncbi.nlm.nih.gov/pubmed/23708738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvt128
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