MicroRNA-126–mediated control of cell fate in B-cell myeloid progenitors as a potential alternative to transcriptional factors

Lineage specification is thought to be largely regulated at the level of transcription, where lineage-specific transcription factors drive specific cell fates. MicroRNAs (miR), vital to many cell functions, act posttranscriptionally to decrease the expression of target mRNAs. MLL-AF4 acute lymphocyt...

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Autori principali: Okuyama, Kazuki, Ikawa, Tomokatsu, Gentner, Bernhard, Hozumi, Katsuto, Harnprasopwat, Ratanakanit, Lu, Jun, Yamashita, Riu, Ha, Daon, Toyoshima, Takae, Chanda, Bidisha, Kawamata, Toyotaka, Yokoyama, Kazuaki, Wang, Shusheng, Ando, Kiyoshi, Lodish, Harvey F., Tojo, Arinobu, Kawamoto, Hiroshi, Kotani, Ai
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746909/
https://ncbi.nlm.nih.gov/pubmed/23893300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220710110
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