A carregar...

How hydrophobic drying forces impact the kinetics of molecular recognition

A model of protein–ligand binding kinetics, in which slow solvent dynamics results from hydrophobic drying transitions, is investigated. Molecular dynamics simulations show that solvent in the receptor pocket can fluctuate between wet and dry states with lifetimes in each state that are long enough...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Mondal, Jagannath, Morrone, Joseph A., Berne, B. J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746852/
https://ncbi.nlm.nih.gov/pubmed/23901110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312529110
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!