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How osmolytes influence hydrophobic polymer conformations: A unified view from experiment and theory

It is currently the consensus belief that protective osmolytes such as trimethylamine N-oxide (TMAO) favor protein folding by being excluded from the vicinity of a protein, whereas denaturing osmolytes such as urea lead to protein unfolding by strongly binding to the surface. Despite there being con...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Mondal, Jagannath, Halverson, Duncan, Li, Isaac T. S., Stirnemann, Guillaume, Walker, Gilbert C., Berne, Bruce J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522754/
https://ncbi.nlm.nih.gov/pubmed/26170324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511780112
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