טוען...
SIRT2 directs the replication stress response through CDK9 deacetylation
Sirtuin 2 (SIRT2) is a sirtuin family deacetylase that directs acetylome signaling, protects genome integrity, and is a murine tumor suppressor. We show that SIRT2 directs replication stress responses by regulating the activity of cyclin-dependent kinase 9 (CDK9), a protein required for recovery fro...
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| Main Authors: | , , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3746840/ https://ncbi.nlm.nih.gov/pubmed/23898190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301463110 |
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