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Cancer metabolism meets systems biology: Pyruvate kinase isoform PKM2 is a metabolic master regulator
Pyruvate kinase activity is controlled by a tightly woven regulatory network. The oncofetal isoform of pyruvate kinase (PKM2) is a master regulator of cancer metabolism. PKM2 engages in parallel, feed-forward, positive and negative feedback control contributing to cancer progression. Besides its met...
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| 第一著者: | |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Medknow Publications & Media Pvt Ltd
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3746496/ https://ncbi.nlm.nih.gov/pubmed/23961261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1477-3163.115423 |
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