Enhanced expression of the M2 isoform of pyruvate kinase is involved in gastric cancer development by regulating cancer‐specific metabolism

Recent studies have indicated that increased expression of the M2 isoform of pyruvate kinase (PKM2) is involved in glycolysis and tumor development. However, little is known about the role of PKM2 in gastric cancer (GC). Therefore, we examined the expression and function of PKM2 in human GC. We eval...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Shiroki, Takeharu, Yokoyama, Misa, Tanuma, Nobuhiro, Maejima, Ryuhei, Tamai, Keiichi, Yamaguchi, Kazunori, Oikawa, Tomoyuki, Noguchi, Tetsuya, Miura, Koh, Fujiya, Tsuneaki, Shima, Hiroshi, Sato, Ikuro, Murata‐Kamiya, Naoko, Hatakeyama, Masanori, Iijima, Katsunori, Shimosegawa, Tooru, Satoh, Kennichi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448664/
https://ncbi.nlm.nih.gov/pubmed/28235245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13211
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