Transgene Expression up to 7 Years in Nonhuman Primates Following Hepatic Transduction with Helper-Dependent Adenoviral Vectors

Helper-dependent adenoviral vectors (HDAd) have been shown to mediate a considerably longer duration of transgene expression than first-generation adenoviral vectors. We have previously shown that transgene expression from HDAd-transduced hepatocytes can persist at high levels for up to 2.6 years in...

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Detalhes bibliográficos
Main Authors: Brunetti-Pierri, Nicola, Ng, Thomas, Iannitti, David, Cioffi, William, Stapleton, Gary, Law, Mark, Breinholt, John, Palmer, Donna, Grove, Nathan, Rice, Karen, Bauer, Cassondra, Finegold, Milton, Beaudet, Arthur, Mullins, Charles, Ng, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746245/
https://ncbi.nlm.nih.gov/pubmed/23902403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2013.071
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