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Progress and prospects: gene therapy for genetic diseases with helper-dependent adenoviral vectors

Preclinical studies in small and large animal models using helper-dependent adenoviral vectors (HDAds) have generated promising results for the treatment of genetic diseases. However, clinical translation is complicated by the dose-dependent, capsid-mediated acute toxic response following systemic v...

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Bibliografische gegevens
Hoofdauteurs: Brunetti-Pierri, N, Ng, P
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668677/
https://ncbi.nlm.nih.gov/pubmed/18288209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2008.14
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