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Progress and prospects: gene therapy for genetic diseases with helper-dependent adenoviral vectors
Preclinical studies in small and large animal models using helper-dependent adenoviral vectors (HDAds) have generated promising results for the treatment of genetic diseases. However, clinical translation is complicated by the dose-dependent, capsid-mediated acute toxic response following systemic v...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3668677/ https://ncbi.nlm.nih.gov/pubmed/18288209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2008.14 |
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