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XIAP inhibits autophagy via XIAP-Mdm2-p53 signalling
The primary role of autophagy is adaption to starvation. However, increasing evidence suggests that autophagy inhibition also plays an important role in tumorigenesis. Upregulation of X-linked inhibitor of apoptosis (XIAP) has been associated to a variety of human cancers, yet the underlying mechani...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
European Molecular Biology Organization
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3746193/ https://ncbi.nlm.nih.gov/pubmed/23749209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.133 |
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