Protein Kinase A Governs a RhoA-RhoGDI Protrusion-Retraction Pacemaker in Migrating Cells

The cyclical protrusion and retraction of the leading edge is a hallmark of many migrating cells involved in processes such as development, inflammation, and tumorigenesis. The molecular identity of signaling mechanisms that control these cycles has remained unknown. Here, we used live cell imaging...

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Main Authors: Tkachenko, Eugene, Sabouri-Ghomi, Mohsen, Pertz, Olivier, Kim, Chungho, Gutierrez, Edgar, Machacek, Matthias, Groisman, Alex, Danuser, Gaudenz, Ginsberg, Mark H.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746034/
https://ncbi.nlm.nih.gov/pubmed/21572420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2231
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