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PROTEOLYSIS OF PLASMA-DERIVED FACTOR V FOLLOWING ITS ENDOCYTOSIS BY MEGAKARYOCYTES FORMS THE PLATELET-DERIVED FACTOR V/VA POOL
BACKGROUND: Central to appropriate thrombin formation at sites of vascular injury is the concerted assembly of plasma- and/or platelet-derived factor Va and factor Xa on the activated platelet surface. While the plasma-derived procofactor, factor V, must be proteolytically activated by α-thrombin to...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3745546/ https://ncbi.nlm.nih.gov/pubmed/23710903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12307 |
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