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Runs of Homozygosity Associated with Speech Delay in Autism in a Taiwanese Han Population: Evidence for the Recessive Model

Runs of homozygosity (ROH) may play a role in complex diseases. In the current study, we aimed to test if ROHs are linked to the risk of autism and related language impairment. We analyzed 546,080 SNPs in 315 Han Chinese affected with autism and 1,115 controls. ROH was defined as an extended homozyg...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Lin, Ping-I, Kuo, Po-Hsiu, Chen, Chia-Hsiang, Wu, Jer-Yuarn, Gau, Susan S-F., Wu, Yu-Yu, Liu, Shih-Kai
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745408/
https://ncbi.nlm.nih.gov/pubmed/23977206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072056
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