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A recessive genetic model and runs of homozygosity in major depressive disorder

Genome-wide association studies (GWASs) of major depressive disorder (MDD) have yet to identify variants that surpass the threshold for genome-wide significance. A recent study reported that runs of homozygosity (ROH) are associated with schizophrenia, reflecting a novel genetic risk factor resultin...

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Detalhes bibliográficos
Publicado no:Am J Med Genet B Neuropsychiatr Genet
Main Authors: Power, Robert A., Keller, Matthew C., Ripke, Stephan, Abdellaoui, Abdel, Wray, Naomi R., Sullivan, Patrick F, Breen, Gerome
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234115/
https://ncbi.nlm.nih.gov/pubmed/24482242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32217
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