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The Nuclear Protein UHRF2 Is a Direct Target of the Transcription Factor E2F1 in the Induction of Apoptosis

The E2F1 transcription factor is active in many types of solid tumors and can function as either an oncogene or tumor suppressor in vivo. E2F1 activity is connected with a variety of cell fates including proliferation, apoptosis, senescence, differentiation, and autophagy, and these effects are medi...

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Autors principals: Lu, Huarui, Hallstrom, Timothy C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745330/
https://ncbi.nlm.nih.gov/pubmed/23833190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.447276
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