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Occludin Is a Direct Target of Thyroid Transcription Factor-1 (TTF-1/NKX2–1)
The thyroid transcription factor 1 gene (TTF-1 or NKX2–1) is essential to lung development; however, it is also a critical factor in lung cancer. TTF-1 is amplified in lung cancers, suggesting that it is a gain-of-function lung oncogene. Conversely, TTF-1 counters epithelial to mesenchymal transitio...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3436544/ https://ncbi.nlm.nih.gov/pubmed/22761434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.367987 |
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