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MiR-365 regulates lung cancer and developmental gene thyroid transcription factor 1
Thyroid transcription factor 1 (TTF-1 or NKX2-1) is an essential fetal lung developmental factor, which can be recurrently activated by gene amplification in adult lung cancer. We have discovered the first microRNA (i.e., miR-365) that directly regulates TTF-1 by interacting with its 3′-untranslated...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3272236/ https://ncbi.nlm.nih.gov/pubmed/22185756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.1.18576 |
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