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MicroRNA-33a Mediates the Regulation of High Mobility Group AT-Hook 2 Gene (HMGA2) by Thyroid Transcription Factor 1 (TTF-1/NKX2–1)

In lung cancers, TTF-1 displays seemingly paradoxical activities. Although TTF-1 is amplified in primary human lung cancers, it inhibits primary lung tumors from metastasizing in a mouse model system. It was reported that the oncogenic proepithelial mesenchymal transition (EMT) high mobility group A...

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Detalles Bibliográficos
Main Authors: Rice, Shawn J., Lai, Shao-Chiang, Wood, Lauren W., Helsley, Kaitlin R., Runkle, E. Aaron, Winslow, Monte M., Mu, David
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675572/
https://ncbi.nlm.nih.gov/pubmed/23625920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.474643
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