Development and validation of RP-HPLC method for sildenafil citrate in rat plasma-application to pharmacokinetic studies

Sildenafil citrate (SIL) is used in the treatment of erectile dysfunction and other chronic disorders. For the pharmacokinetic investigation of SIL we developed a simple and sensitive method for the estimation of SIL in rat plasma by reverse phase high-performance liquid chromatography (RP-HPLC). Th...

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Main Authors: Tripathi, A.S., Sheikh, I., Dewani, A.P., Shelke, P.G., Bakal, R.L., Chandewar, A.V., Mazumder, P.M.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745091/
https://ncbi.nlm.nih.gov/pubmed/23960848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2012.09.003
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