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Specialized sorting of GLUT4 and its recruitment to the cell surface are independently regulated by distinct Rabs

Adipocyte glucose uptake in response to insulin is essential for physiological glucose homeostasis: stimulation of adipocytes with insulin results in insertion of the glucose transporter GLUT4 into the plasma membrane and subsequent glucose uptake. Here we establish that RAB10 and RAB14 are key regu...

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Détails bibliographiques
Auteurs principaux: Sadacca, L. Amanda, Bruno, Joanne, Wen, Jennifer, Xiong, Wenyong, McGraw, Timothy E.
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744946/
https://ncbi.nlm.nih.gov/pubmed/23804653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-02-0103
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