eIF5A Promotes Translation of Polyproline Motifs

Translation factor eIF5A, containing the unique amino acid hypusine, was originally shown to stimulate methionyl-puromycin synthesis, a model assay for peptide bond formation. More recently, eIF5A was shown to promote translation elongation; however, its precise requirement in protein synthesis has...

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Main Authors: Gutierrez, Erik, Shin, Byung-Sik, Woolstenhulme, Christopher J., Kim, Joo-Ran, Saini, Preeti, Buskirk, Allen R., Dever, Thomas E.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744875/
https://ncbi.nlm.nih.gov/pubmed/23727016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.04.021
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