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X-inactivation and X-reactivation: epigenetic hallmarks of mammalian reproduction and pluripotent stem cells

X-chromosome inactivation is an epigenetic hallmark of mammalian development. Chromosome-wide regulation of the X-chromosome is essential in embryonic and germ cell development. In the male germline, the X-chromosome goes through meiotic sex chromosome inactivation, and the chromosome-wide silencing...

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Autors principals: Payer, Bernhard, Lee, Jeannie T., Namekawa, Satoshi H.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744832/
https://ncbi.nlm.nih.gov/pubmed/21667284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-011-1024-7
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