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Two-Step Imprinted X Inactivation: Repeat versus Genic Silencing in the Mouse

Mammals compensate for unequal X-linked gene dosages between the sexes by inactivating one X chromosome in the female. In marsupials and in the early mouse embryo, X chromosome inactivation (XCI) is imprinted to occur selectively on the paternal X chromosome (X(P)). The mechanisms and events underly...

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Autors principals: Namekawa, Satoshi H., Payer, Bernhard, Huynh, Khanh D., Jaenisch, Rudolf, Lee, Jeannie T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897575/
https://ncbi.nlm.nih.gov/pubmed/20404085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00227-10
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