MELK-Dependent FOXM1 Phosphorylation is Essential for Proliferation of Glioma Stem Cells

Glioblastoma multiforme (GBM) is a life-threatening brain tumor. Accumulating evidence suggests that eradication of glioma stem-like cells (GSCs) in GBM is essential to achieve cure. The transcription factor FOXM1 has recently gained attention as a master regulator of mitotic progression of cancer c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Joshi, Kaushal, Banasavadi-Siddegowda, Yeshavanth, Mo, Xiaokui, Kim, Sung-Hak, Mao, Ping, Kig, Cenk, Nardini, Diana, Sobol, Robert W, Chow, Lionel ML, Kornblum, Harley I, Waclaw, Ronald, Beullens, Monique, Nakano, Ichiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley Subscription Services, Inc., A Wiley Company 2013
Schlagworte:
Cancer Stem Cells
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744761/
https://ncbi.nlm.nih.gov/pubmed/23404835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1358
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