Chromatin-to-nucleoprotamine transition is controlled by the histone H2B variant TH2B

The conversion of male germ cell chromatin to a nucleoprotamine structure is fundamental to the life cycle, yet the underlying molecular details remain obscure. Here we show that an essential step is the genome-wide incorporation of TH2B, a histone H2B variant of hitherto unknown function. Using mou...

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Bibliografiska uppgifter
Huvudupphovsmän: Montellier, Emilie, Boussouar, Fayçal, Rousseaux, Sophie, Zhang, Kai, Buchou, Thierry, Fenaille, François, Shiota, Hitoshi, Debernardi, Alexandra, Héry, Patrick, Curtet, Sandrine, Jamshidikia, Mahya, Barral, Sophie, Holota, Hélène, Bergon, Aurélie, Lopez, Fabrice, Guardiola, Philippe, Pernet, Karin, Imbert, Jean, Petosa, Carlo, Tan, Minjia, Zhao, Yingming, Gérard, Matthieu, Khochbin, Saadi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2013
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744726/
https://ncbi.nlm.nih.gov/pubmed/23884607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.220095.113
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