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Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters

Recently discovered histone lysine acylation marks increase the functional diversity of nucleosomes well beyond acetylation. Here, we focus on histone butyrylation in the context of sperm cell differentiation. Specifically, we investigate the butyrylation of histone H4 lysine 5 and 8 at gene promote...

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Pubblicato in:Mol Cell
Autori principali: Goudarzi, Afsaneh, Zhang, Di, Huang, He, Barral, Sophie, Kwon, Oh Kwang, Qi, Shankang, Tang, Zhanyun, Buchou, Thierry, Vitte, Anne-Laure, He, Tieming, Cheng, Zhongyi, Montellier, Emilie, Gaucher, Jonathan, Curtet, Sandrine, Debernardi, Alexandra, Charbonnier, Guillaume, Puthier, Denis, Petosa, Carlo, Panne, Daniel, Rousseaux, Sophie, Roeder, Robert G., Zhao, Yingming, Khochbin, Saadi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850424/
https://ncbi.nlm.nih.gov/pubmed/27105113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.03.014
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