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Chromatin-to-nucleoprotamine transition is controlled by the histone H2B variant TH2B
The conversion of male germ cell chromatin to a nucleoprotamine structure is fundamental to the life cycle, yet the underlying molecular details remain obscure. Here we show that an essential step is the genome-wide incorporation of TH2B, a histone H2B variant of hitherto unknown function. Using mou...
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3744726/ https://ncbi.nlm.nih.gov/pubmed/23884607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.220095.113 |
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