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Defining the roles of individual residues in the single-stranded DNA binding site of PcrA helicase
Crystal structures and biochemical analyses of PcrA helicase provide evidence for a model for processive DNA unwinding that involves coupling of single-stranded DNA (ssDNA) tracking to a duplex destabilization activity. The DNA tracking model invokes ATP-dependent flipping of bases between several p...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC37447/ https://ncbi.nlm.nih.gov/pubmed/11459979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.131009598 |
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