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Defining the roles of individual residues in the single-stranded DNA binding site of PcrA helicase

Crystal structures and biochemical analyses of PcrA helicase provide evidence for a model for processive DNA unwinding that involves coupling of single-stranded DNA (ssDNA) tracking to a duplex destabilization activity. The DNA tracking model invokes ATP-dependent flipping of bases between several p...

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Detalles Bibliográficos
Main Authors: Dillingham, Mark S., Soultanas, Panos, Wiley, Paul, Webb, Martin R., Wigley, Dale B.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC37447/
https://ncbi.nlm.nih.gov/pubmed/11459979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.131009598
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