Subunit Vaccine Consisting of Multi-Stage Antigens Has High Protective Efficacy against Mycobacterium tuberculosis Infection in Mice

To search for more effective tuberculosis (TB) subunit vaccines, antigens expressed in different growth stages of Mycobacterium tuberculosis (M. tuberculosis), such as RpfE (Rv2450c) produced in the stage of resuscitation, Mtb10.4 (Rv0288), Mtb8.4 (Rv1174c), ESAT6 (Rv3875), Ag85B (Rv1886c) mainly se...

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Autors principals: Xin, Qi, Niu, Hongxia, Li, Zhi, Zhang, Guoping, Hu, Lina, Wang, Bingxiang, Li, Jingjing, Yu, Hongjuan, Liu, Wanbo, Wang, Yue, Da, Zejiao, Li, Ruiying, Xian, Qiaoyang, Wang, Yong, Zhang, Ying, Jing, Tao, Ma, Xingming, Zhu, Bingdong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744459/
https://ncbi.nlm.nih.gov/pubmed/23967337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072745
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