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ATP bound to the origin recognition complex is important for preRC formation

The origin recognition complex (ORC) binds origins of replication and directs the assembly of a higher order protein complex at these sites. ORC binds and hydrolyzes ATP in vitro. ATP binding to the largest subunit of ORC, Orc1p, stimulates specific binding to origin DNA; however, the function of AT...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Klemm, Richard D., Bell, Stephen P.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2001
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC37444/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11459976/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.131006898
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