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ATP bound to the origin recognition complex is important for preRC formation
The origin recognition complex (ORC) binds origins of replication and directs the assembly of a higher order protein complex at these sites. ORC binds and hydrolyzes ATP in vitro. ATP binding to the largest subunit of ORC, Orc1p, stimulates specific binding to origin DNA; however, the function of AT...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The National Academy of Sciences
2001
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC37444/ https://ncbi.nlm.nih.gov/pubmed/11459976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.131006898 |
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