ATP bound to the origin recognition complex is important for preRC formation
The origin recognition complex (ORC) binds origins of replication and directs the assembly of a higher order protein complex at these sites. ORC binds and hydrolyzes ATP in vitro. ATP binding to the largest subunit of ORC, Orc1p, stimulates specific binding to origin DNA; however, the function of AT...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC37444/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11459976/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.131006898 |
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