Impact of antibody quality and anamnestic response on viremia control post-challenge in a combined Tat/Env vaccine regimen in rhesus macaques

Previously, priming rhesus macaques with Adenovirus type 5 host range mutant-recombinants encoding Tat and Env and boosting with Tat and Env protein in MPL-SE controlled chronic viremia by 4 logs following homologous intravenous SHIV(89.6P) challenge. Here we evaluated Tat, Env, and Tat/Env regimens...

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Autori principali: Demberg, Thorsten, Brocca-Cofano, Egidio, Kuate, Seraphin, Aladi, Stanley, Vargas-Inchaustegui, Diego A., Venzon, David, Kalisz, Irene, Kalyanaraman, V.S., Lee, Eun Mi, Pal, Ranajit, DiPasquale, Janet, Ruprecht, Ruth M., Montefiori, David C., Srivastava, Indresh, Barnett, Susan W., Robert-Guroff, Marjorie
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744165/
https://ncbi.nlm.nih.gov/pubmed/23528732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.02.024
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