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Iterative Molecular Dynamics—Rosetta Protein Structure Refinement Protocol to Improve Model Quality

[Image: see text] Rosetta is one of the prime tools for high resolution protein structure refinement. While its scoring function can distinguish native-like from non-native-like conformations in many cases, the method is limited by conformational sampling for larger proteins, that is, leaving a loca...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lindert, Steffen, Meiler, Jens, McCammon, J. Andrew
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2013
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744128/
https://ncbi.nlm.nih.gov/pubmed/23956701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct400260c
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