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Developing and Validating Continuous Genomic Signatures in Randomized Clinical Trials for Predictive Medicine

PURPOSE: It is highly challenging to develop reliable diagnostic tests to predict patients’ responsiveness to anticancer treatments on clinical endpoints before commencing the definitive phase III randomized trial. Development and validation of genomic signatures in the randomized trial can be a pro...

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Detalhes bibliográficos
Main Authors: Matsui, Shigeyuki, Simon, Richard, Qu, Pingping, Shaughnessy, John D., Barlogie, Bart, Crowley, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744097/
https://ncbi.nlm.nih.gov/pubmed/22927484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-1206
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