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Developing and Validating Continuous Genomic Signatures in Randomized Clinical Trials for Predictive Medicine

PURPOSE: It is highly challenging to develop reliable diagnostic tests to predict patients’ responsiveness to anticancer treatments on clinical endpoints before commencing the definitive phase III randomized trial. Development and validation of genomic signatures in the randomized trial can be a pro...

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Bibliografiske detaljer
Main Authors: Matsui, Shigeyuki, Simon, Richard, Qu, Pingping, Shaughnessy, John D., Barlogie, Bart, Crowley, John
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744097/
https://ncbi.nlm.nih.gov/pubmed/22927484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-1206
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