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Regulation of Cullin-RING ubiquitin ligase 1 by Spliceosome-associated protein 130 (SAP130)

Cullin-RING ubiquitin ligases (CRLs) mediate the ubiquitination of numerous protein substrates and target them for proteasomal degradation. The function of CRLs is under tight regulation by Cullin-binding proteins. It has been reported that the Spliceosome-associated protein 130 (SAP130/SF3b-3) bind...

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Autors principals: Cordero-Espinoza, Lucia, Hagen, Thilo
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744076/
https://ncbi.nlm.nih.gov/pubmed/23951410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20134374
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