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Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration
Transcription factor Nrf2 and its repressor Keap1 regulate a network of cytoprotective genes involving more than 1% of the genome, their best known targets being drug-metabolizing and antioxidant genes. Here we demonstrate a novel role for this pathway in directly regulating mitochondrial bioenerget...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3744067/ https://ncbi.nlm.nih.gov/pubmed/23951401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20134853 |
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